Chat with us, powered by LiveChat MN553 Unit 9 Practice Quiz | acewriters
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1. Question
:
Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading
to:

A need to monitor drugs metabolized by 2D6 for
toxicity
Increased dosages needed of drugs metabolized
by 2D6, such as the selective serotonin reuptake inhibitors
Decreased conversion of codeine to morphine by
CYP 2D6
The need for lowered dosages of drugs, such as
beta blockers

Question 2. Question
:
Rifampin is a nonspecific CYP450 inducer that may:

Lead to toxic levels of rifampin and must be
monitored closely
Cause toxic levels of drugs, such as oral
contraceptives, when coadministered
Induce the metabolism of drugs, such as oral
contraceptives, leading to therapeutic failure
Cause nonspecific changes in drug metabolism

Question 3. Question
:
Inhibition of P-glycoprotein by a drug such as quinidine may
lead to:

Decreased therapeutic levels of quinidine
Increased therapeutic levels of quinidine
Decreased levels of a coadministered drug,
such as digoxin, that requires P-glycoprotein for absorption and elimination
Increased levels of a coadministered drug,
such as digoxin, that requires P-glycoprotein for absorption and elimination

Question 4. Question
:
Warfarin resistance may be seen in patients with VCORC1
mutation, leading to:

Toxic levels of warfarin building up
Decreased response to warfarin
Increased risk for significant drug
interactions with warfarin
Less risk of drug interactions with warfarin

Question 5. Question
:
Pharmacogenetic testing is required by the U.S. Food and Drug
Administration prior to prescribing:

Erythromycin
Digoxin
Cetuximab
Rifampin

Question 6. Question
:
Carbamazepine has a Black Box Warning recommending testing
for the HLA-B*1502 allele in patients with Asian ancestry prior to starting
therapy due to:

Decreased effectiveness of carbamazepine in
treating seizures in Asian patients with the HLA-B*1502 allele
Increased risk for drug interactions in Asian
patients with the HLA-B*1502 allele
Increased risk for Stevens-Johnson syndrome in
Asian patients with HLA-B*1502 Allele
Patients who have the HLA-B*1502 allele being
more likely to have a resistance to carbamazepine

Question 7. Question
:
A genetic variation in how the metabolite of the cancer drug
irinotecan SN-38 is inactivated by the body may lead to:

Decreased effectiveness of irinotecan in the
treatment of cancer
Increased adverse drug reactions, such as
neutropenia
Delayed metabolism of the prodrug irinotecan
into the active metabolite SN-38
Increased concerns for irinotecan being
carcinogenic

Question 8. Question
:
A good history of herb and supplement use is critical before
prescribing because approximately ____ % of patients in the United States are
using herbal products.

10
5
38
70

Question 9. Question
:
A potential harmful effect on patients who take some herbal
medication is:

Constipation
Lead poisoning
Diarrhea
Life-threatening rash

Question 10. Question
:
A thorough understanding of herbs is critical to patient
safety. An example is the use of cinnamon to treat type II diabetes. It is
important the patient uses Ceylon cinnamon, as the commercially available
cassia cinnamon contains:

Coumadin, which may lead to bleeding problems
Coumarin, which can cause liver and kidney
damage
Cinnamic aldehyde, which is toxic to the
kidney
Cinnamate eugenol, which is toxic to the liver

Question 11. Question
:
Traditional Chinese medicine utilizes yin (cooling) versus
yang (warming) in assessing and treating disease. Menopause is considered a
time of imbalance, therefore the Chinese herbalist would prescribe:

Herbs which are yang in nature
Herbs that are yin in nature
Ginger
Golden seal

Question 12. Question
:
According to traditional Chinese medicine, if a person who
has a fever is given a herb that is yang in nature, such as golden seal, the
patient’s illness will:

Get worse
Get better
Not be adequately treated
Need additional herbs to treat the yang

Question 13. Question
:
In Ayurvedic medicine, treatment is based on the patient’s
dominant dosha, which is referred to as the person’s:

Vata
Pitta
Kapha
Prakriti

Question 14. Question
:
When melatonin is used to induce sleep, the recommendation is
that the patient:

Take 10 mg 30 minutes before bed nightly
Take 1 to 5 mg 30 minutes before bed nightly
Not take melatonin more than three nights a
week
Combine melatonin with zolpidem (Ambien) for
the greatest impact on sleep

Question 15. Question
:
In the United States, over-the-counter drugs are regulated
by:

No one. There is no oversight for over-the-counter
medications.
The U.S. Food and
Drug Administration Center for Drug Evaluation and Research
The U.S. Drug Enforcement Administration
MedWatch

Question 16. Question
:
As drugs near the end of their patent, pharmaceutical
companies may apply for the drug to change to over-the-counter status in order
to:

Get a new patent for the over-the-counter form
of the drug
Lower the costs because most prescription
benefit plans do not cover generics
Market the drug to a whole new population, as
they are able to market to patients instead of just providers
Continue to make large profits from their
blockbuster brand-name drug

Question 17. Question
:
The ailment that generates the greatest over-the-counter
annual drug sales is:

Constipation
Cough and colds
Heartburn
Acute and chronic pain

Question 18. Question
:
Common over-the-counter pain relievers such as acetaminophen
or ibuprofen:

Are always safer for the patient than
prescription pain medication
Are harmful if taken in higher than recommended
amounts
Have minimal interaction with prescription
medications
Should never be given to children unless
recommended by their provider

Question 19. Question
:
When obtaining a drug history from Harold, he gives you a
complete list of his prescription medications. He denies taking any other
drugs, but you find that he occasionally takes aspirin for his arthritis flare
ups. This is an example of:

His appropriately only telling you about his
regularly prescribed medications
His hiding information regarding his
inappropriate use of aspirin from you
A common misconception that intermittently
taken over-the counter medications are not an important part of his drug
history
A common misuse of over-the-counter aspirin

Question 20. Question
:
Michael asks you about why some drugs are over-the-counter
and some are prescription. You explain that in order for a drug to be approved
for over-the-counter use the drug must:

Be safe and labeled for appropriate use
Have a low potential for abuse or misuse
Be taken for a condition the patient can
reliably self-diagnose
All of the above

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